The Firefox performance regression introduced into the codebase on 2012-09-29 and present in FF v18, v19, and Nightly versions is much more serious than I previously thought.
Basically FF versions after v16 are now almost unusable running NextGen models of any complexity for longer than 30s.
There are several active Mozilla issues that people are working on. This is my original bug report:
- [Bug 791699] Slow setting of attributes on SVG elements due to time spent in region operations on this molecular dynamics simulation
And the other bug reports resolving this issue depends on: